Reading these messages about Prozac and weight gain are making me jump for joy. I was on Prozaz over 10 years ago for about 9 months and I lost 10lbs. After my second child was born I couldn't lose the extra weight and I had bouts of depression and anxiety that got to the point that I finally went back on Prozac. Well, it's been two years since I have been on it and initially I lost about 5lbs. BUT, all of a sudden I have gains 15 lbs and I am more depressed than ever! I was convinced I had no metabolism or a thyroid problem but my results came back negative. I asked my doctor about it and he said that sometimes people gain weight on Prozac because they eat more because they are happier. Let me tell you, I am so glad I know that this is truly an issue with a lot of people out there. I have actually increased my dosage over the past year thinking that would increase my metabolism. After reading these testimonials, I am going to try to wean myself off the drug. If anyone out there has any other comments or suggestions on this issue, I would love to hear about them!