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Date Posted: 20:09:34 04/18/02 Thu
Author: terry
Author Host/IP: NoHost / 66.84.232.176
Subject: Encouraging...I wonder...
In reply to: Susie 's message, "For Those Waiting for Pegasys" on 18:36:53 04/18/02 Thu

Treatment naive? Meaning never having treated, I assume. Do you know if the numbers go down much for someone who's tried peg-intron first? Thanks!

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Replies:

[> [> Re: Encouraging...I wonder... -- Susie, 20:25:30 04/18/02 Thu (bgp425870bgs.union01.nj.comcast.net/68.36.197.75)

Yup, that is exactly what treatment naive means. There have not been studies done yet for people who have already tried combo and failed but the docs believe the numbers will be very low. Dr. Shiffman told me he expects about a 13% clearnance rate in those who failed combo treatment. But hey, someone has to be in that 13%. I know I'm going to try.


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[> [> [> Re: Encouraging...I wonder...OUCH, that was short high. -- sg, 20:30:17 04/18/02 Thu (Toronto-HSE-ppp3663134.sympatico.ca/65.95.154.237)


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[> [> [> [> no sh*t, huh!! big drop. How's thangs sg? -- terry, 20:33:06 04/18/02 Thu (NoHost/66.84.232.176)


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[> [> [> [> [> Re: Blew my high. Things are gggreeaaat. So far. -- sg, 20:47:53 04/18/02 Thu (Toronto-HSE-ppp3663134.sympatico.ca/65.95.154.237)


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[> [> [> Re: Encouraging...I wonder...SUSIE do U know?? -- sg, 20:43:37 04/18/02 Thu (Toronto-HSE-ppp3663134.sympatico.ca/65.95.154.237)

Hi Susie,

When Dr Shiffman (I'm not familiar with the name), said he expected a 13% clearance rate for those who failed previous combo(3x week)was this in reference to PEGASYS?

Also, if you know (OK if you don't), am I correct to assume that failed equals - did not respond, and responded but then relapsed (cat came back)?

sg


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[> [> [> [> Re: Encouraging...I wonder... -- Susie, 20:46:08 04/18/02 Thu (bgp425870bgs.union01.nj.comcast.net/68.36.197.75)

Failed means never got to undetected. We were not talking about relapsers who have a much better chance than us flunkies, although not as good as naive patients. Dr. Schiffman works almost exclusively with Pegasys and he is the head of hepatology at Medical College of Virginia. He is very well respected in the States.


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[> [> [> [> [> Re: Encouraging...I wonder...OK, I'm back in the groove. -- sg, 20:50:20 04/18/02 Thu (Toronto-HSE-ppp3663134.sympatico.ca/65.95.154.237)


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[> [> [> [> [> [> I'm Glad :-) -- Susie, 21:25:46 04/18/02 Thu (bgp425870bgs.union01.nj.comcast.net/68.36.197.75)


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