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TB Drugs -- Normelena, 17:09:29 12/17/03 Wed [1]

Think TB think Rest In Peace Everyone

Rifampin
Isoniazid
Pyrazinamide
Ethambutol

Also E for Eyes b/c Ethambutol adverse effect is optic neuritis (red light = green light)

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[> Re: TB Drugs -- Michelle, 16:34:13 12/08/05 Thu [1]

Or Rest In Peace Edgar (Allen Poe, who had TB)

for literature nuts.

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CBV regimen for testicular cancer -- Andrew, 15:47:31 12/13/04 Mon [1]

CBV regimen is given for testicular cancer, so to remember it, just think about Very Cancerous Balls

V = vinblastin
C = cisplatin
B = bleomycin

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A Vancomycin Adverse effect -- Kori, 21:41:25 12/08/04 Wed [1]

Think of the Chris Farley's SNL sketch "VAN down by the river" and how his face gets really red as he goes along and the level of his voice gets higher...

Van voice level = Vancomycin serum level
when it gets to high it leads to
red faced Chris Farley = Red Man Syndrome

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Eicosanoide -- Monish, 16:29:25 12/17/03 Wed [1]

Here is how i remember the general properties of eicosanoids:

Good ones: EI-EI-o
(like the old mcdonald song, how harmful can he be? stands for PGE and PGI by the way, which tend to do good stuff)

Bad ones: Luke's Feet are Toxic or Luke is Fucking Toxic
(whichever you like. This stands for Luekotrienes, PGF, and Thromboxane. They do bad stuff, just like Luke..jk btw this is just a mneumonic..Amy's feet are really more toxic)

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Procarbazine -- Stasia, 15:53:52 12/17/03 Wed [1]

"Mop up the wine, beer, and yogurt as part of your pro-carb diet"

MOPP--used in Hodgkins (Procarbazine also used for for CVPP regimen, small cell, malignant melanoma and brain tumors)

Wine, Beer, Yogurt--(and cheese): Procarbazine is a weak MAO inhibitor so hypertension can occur if exposed to sympathomimetic agents or tyramine foods

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Luminal amebicides -- Deb, 15:38:58 12/17/03 Wed [1]

What're ya gonna give a pregnant MOM for amebiasis:
paroMOMycin

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minor actions of Anthracyclines -- Tom, 11:09:13 12/17/03 Wed [3]

for the minor actions, think TOM: Topoisomerase II inhibitor, O2-radicals, and Membrane permeability

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[> Natural Products -- Deb, 12:40:31 12/17/03 Wed [1]

>for the minor actions, think TOM: Topoisomerase II
>inhibitor, O2-radicals, and Membrane permeability

just have to get your own name in there, huh ;)

Natural Products: VP DEB

Vinca Alkaloids - Vincristine/Vinblastine
Paclitaxel

Doxorubicin/Daunorubicin
Etoposide
Bleomycin

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[> [> Re: Natural Products -- Sumit, 14:42:08 12/17/03 Wed [1]

While we are on our own names, need I mention my name for Sumatriptan - cures migraines, and isn't for the weak hearted.

Sumit

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[> [> [> Re: Natural Products -- Suma Dit, 14:43:17 12/17/03 Wed [1]

Or should I have signed that "Suma Dit," that might have been better.

Suma Dit

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Cyt P450 inhibitors -- Jen Lai, 12:32:17 12/17/03 Wed [1]

Think of Cyt P450 being extremely pissed off because it gets inhibited by so many drugs. Every fucking person takes advantage of ME!

E: Erythromycin
F: Fungal azoles
P: Procarbazine
T: TMP-SMX
O: Nothing
Me: Metronidazole

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[> Re: Cyt P450 inhibitors -- Jen Lai, 12:34:23 12/17/03 Wed [1]

Oops, forgot the A... A: Allopurinol

>Think of Cyt P450 being extremely pissed off because
>it gets inhibited by so many drugs. Every fucking
>person takes advantage of ME!
>
>E: Erythromycin
>F: Fungal azoles
>P: Procarbazine
>T: TMP-SMX
>O: Nothing
>Me: Metronidazole

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biliary secreted antibiotics -- rob g, 12:06:22 12/17/03 Wed [1]

this is how i remember them:
Donny And Ryan Eat (fill in this one with a word that begins with C), thats donny hannoun and william ryan spiker, my glorious roommates

Doxycycline
Ampicillin
Rifampin
Erythromycin
Ceftriaxone

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for Paclitaxel -- Tom, 11:01:33 12/17/03 Wed [1]

think of "taxing" - having sex with a girl
Paclitaxel is for treating ovarian and breast cancer

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[> Etoposide -- Tom, 11:05:53 12/17/03 Wed [1]

think of 3 T's: eToposide, topoisomerase II, and testicular cancer

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Aminoglycosides -- Stevo, 10:51:09 12/17/03 Wed [1]

GaNgSTA

Gentamicin
Neomycin
Streptomycin
Tobramycin
Amikacin

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Mechanism for Iron Poisoning -- Stasia, 10:44:21 12/17/03 Wed [1]

Pumping IRON burns FAT and SUGAR and leads to LACTIC ACID buildup.

IRON induces LIPID peroxidation in mitochondria, inhibiting electron transport. This leads to compensatory GLYCOLYSIS and production of LACTIC ACID.

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Side effects of all anticancer drugs -- Stevo, 03:26:06 12/17/03 Wed [1]

BAN ICM

1. B - Bone marrow suppression
2. A - Alopecia
3. N - Nausea
4. I - Immunosuppressive
5. C - Cytotoxic
6. M - Mutagenic

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[> Re: Side effects of all anticancer drugs -- Sumit, 09:37:15 12/17/03 Wed [1]

Dude, this is money!!

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Therapy for dioxin poisoning -- Jen, 08:29:47 12/17/03 Wed [1]

Ah, alas, you will die soon if you hit a cholesterol mine.

ah, alas = toxicity is caused by induction of arylhydrocarbon hydroxylase (ah) and ALA synthase (alas)
die = dioxin
cholesterol mine = cholestyramine

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Therapy for cyanide poisoning -- Jen, 08:23:50 12/17/03 Wed [1]

Instead of giving cyanide to the person who owes you a lot of money, go to an ATM.

A = Amyl nitrite
T = sodium Thiosulfate
M = Methylene blue

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Adverse effect of bleomycin -- Jen, 08:18:36 12/17/03 Wed [1]

Leo the bee likes to build honeycombs in your lungs.

Leo the bee = bleomycin
honeycombs in your lungs = pulmonary fibrosis

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Don't Depress Bone Marrow -- Deb, 03:50:54 12/17/03 Wed [1]

SaVe Bone Growth

Streptozotocin
Vincristine
Bleomycin/Busulfan
Glucocorticoids

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Clinical uses for gentamicin -- Tiney-bopper, 03:34:15 12/17/03 Wed [1]

GENTly ENTER your STAFF

GENT: Gentamicin used to treat the following two...
ENTER: Enterococcal infxn
STAFF=STAPH = Staph infxn.

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Sulfonamides Adverse Effects -- Amelia, 01:56:48 12/17/03 Wed [1]

Picture Steven's johnson with a skin rash and swollen head - Stevens Johnson syndrome, skin rash, encephalopathy due to bile accumulation in brain from albumin separation.

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[> Re: Sulfonamides Adverse Effects -- Sumit, 02:33:54 12/17/03 Wed [1]

>Picture Steven's johnson with a skin rash and swollen
>head - Stevens Johnson syndrome, skin rash,
>encephalopathy due to bile accumulation in brain from
>albumin separation.

Yep and you can think of Steven Johnson as a surfer (sulfur drug - sulfonamide).

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HANDOUTS -- Deb, 01:43:22 12/17/03 Wed [1]

just wanted to let you guys know that there is a difference between the handout we were given in our boxes and the one that's posted online. the one online doesn't point out some of the optional ones we have in our printed handout (i.e. dactinomycin plicamycin mitomycin L-asparaginase are optional)

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[> Re: HANDOUTS -- Sumit, 01:46:09 12/17/03 Wed [1]

>just wanted to let you guys know that there is a
>difference between the handout we were given in our
>boxes and the one that's posted online. the one
>online doesn't point out some of the optional ones we
>have in our printed handout (i.e. dactinomycin
>plicamycin mitomycin L-asparaginase are optional)

Damn and I even came up with a mnemonic for Plicamycin......well I guess all in the name of science.

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Antineoplastic Hormones -- Deb, 01:41:48 12/17/03 Wed [1]

Hormones:
TAPED GoLF

Tamoxifen
Aminoglutethimide
Prednisone
Ethinyl estradiol
Diethylstilbesterol

GOserelin
Leuprolide
Flutamide

Note that the GoLF is a combo that is administered together for the whole feedback inhibition stuff

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Vinca Alkaloids -- Sumit, 01:29:10 12/17/03 Wed [1]

Vin(ce) and Matt blast crystal and Cristine.
And you can think of Cristine doing everyone (broad applications), and you only blast limited things (vinblastine-limited use).

Sumit

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[> Re: Vinca Alkaloids -- Sumit, 01:40:37 12/17/03 Wed [1]

>Vin(ce) and Matt blast crystal and Cristine.
>And you can think of Cristine doing everyone (broad
>applications), and you only blast limited things
>(vinblastine-limited use).
>
>Sumit
Oh yeah Matt is for Metaphase

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herpes antiviral drugs -- Deb, 01:28:03 12/17/03 Wed [1]

Fucking GAVe me herpes

Foscarnet (optional, but adds some flavor)

Ganciclovir
Acyclovir
Vidarabine

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pliCAmycin -- Sumit, 01:19:42 12/17/03 Wed [1]

PliCAmycin - CA (calcium) - need I say more?

Sumit

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Bile Secreted Drugs -- Sumit, 01:17:59 12/17/03 Wed [1]

See the post by Luke for this also, somehow it got posted under Nitrosoureas??

But the letters for the name of bile secreted drugs can be rearranged to "A red can."

Sumit

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Methotrexate -- Sumit, 23:26:29 12/16/03 Tue [1]

MetHO trexate - I met a ho fool - pure poly. Luke did her too, but didn't penetrate.

So fool - folate
pure - inhibits purine synthesis
poly - polyglutamate
Luke - leucovorin
didn't penetrate - doesn't penetrate tumor cell or penetrate into DNA/RNA.

Sumit

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[> Re: Methotrexate -- Deb, 00:42:08 12/17/03 Wed [1]

>Luke - leucovorin
>didn't penetrate - doesn't penetrate tumor cell or
>penetrate into DNA/RNA.

just to clarify:
leucovorin doesn't penetrate the tumor cell
methotrexate doesn't penetrate DNA/RNA

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Nitrosoureas -- Sumit, 23:21:17 12/16/03 Tue [2]

Ok here is for the nitrosoureas:

LoSe Car - Imagine a car that's shaped like a brain and is got fat and goo all over it. It has two passengers - alka and carba (the repair man).

So the LoSe Car (Lomustine, Semustine, Carmustine) - brain for brain cancer - fat (lipophilic). Alkylating species and carbamoylating species. Repair man (messes with DNA-repair enzymes).

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[> Re: Nitrosoureas -- Mike Favazza, 23:44:02 12/16/03 Tue [1]

I think of "stupid Carlose"

Car - mustine
Lo - mustine
Se - mustine

has a CNS adverse effect (messes with the brain)

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[> Re: Nitrosoureas -- Luke, 00:26:51 12/17/03 Wed [1]

Donny (hanoon) And Ryan (spiker) Eat Cock
Doxycycline, Ampicillin, Rifampin, Erythromycin, Ceftriaxone.
These are biliary excreted drugs.
I have to give credit to Rob Gourney (Donny and Ryans roommate), and also apologize to Donny and Ryan but yet thank them because we will NEVER forget biliary excreted drugs. Good night

Luke

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Kwitka's Cancer Song [hope Kwitka doesn't mind.] -- Deb, 23:35:27 12/16/03 Tue [1]

It’s beginning to look a lot like cancer
NITROGEN MUSTARDS
Take a look at MECHLORETHAMINE
Cross-linking guanines again
With CYCLOPHOSPHAMINE also you know

It’s beginning to look a lot like CARMUSTINE
And other NITROSOURIAS
But the non-synthetic to see is the STREPTOZO-TOCIN that will be on your diabetic door
A pair of SEMUSTINE and LOMUSTINE is the wish for brain tumors then
And platinum compounds like CARBOPLATIN is substituted for CIS nephrotoxin
And PROCARBAZINE can hardly wait to treat the Hodgkin’s

It’s beginning to look a lot like natural products
VINCA ALKALOIDS
That PACLITAXEL blocks cells in mitosis as
well
But does ETOPOSIDE bind to tublin? No!

It’s beginning to look a lot like ANTHRACYCLINES
BLEOMYCIN for a start
And the thing that will to DNA cling is that DOXORUBICIN
Just like DANORUBICIN
Right within G2!



Disclaimers:
1. Some of it may not seem to rhyme because I have no idea how to correctly pronounce these drugs, but it rhymes with the original Christmas lyrics in my head and that is what counts!
2. Streptozotocin causes diabetes, hence the diabetic door
3. Carboplatin is used in cases where cisplatin is toxic
4. Doxorubicin and Danorubicin don’t really “cling” to DNA but they do intercalate

It’s beginning to look a lot like Christmas
Everywhere you go
Take a look in the five and ten
Glistening once again
With candy canes and silver lanes aglow

It’s beginning to look a lot like Christmas
Toys in every store
But the prettiest sight to see is the holly that will be on your own front door
A pair of hop-a-long boot and a pistol that shoots is the wish of Barney and Ben
Dolls that can talk and will go for a walk is the hope of Janice and Jen
And Mom and Dad can hardly wait for school to start again

It’s beginning to look a lot like Christmas
Everywhere you go
There’s a tree in the grand hotel, one in the park as well
The sturdy kind that doesn’t mind the snow

It’s beginning to look a lot like Christmas

Soon the bells will start
And the thing that will make them ring is the
carol that you sing
Right within your heart
Right within your heart!

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Streptozotocin -- Sumit, 23:27:49 12/16/03 Tue [1]

Zoto reminds me of Zoro - so Zoro is fighting and get tired because he is a diabetic (you didn't know that did you).

So diabetogenic, taken up by B-cells, and is for pancreatic islet cell cancer.

Sumit

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Lead Poisoning -- Sumit, 23:24:14 12/16/03 Tue [1]

Lead is treated by ED the Dime and Penny man.

ED - EDTA
dime - dimercaprol
penny - penicillamine.

Sumit

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HEY -- Sumit, 23:03:23 12/16/03 Tue [1]

Ok, so put your mnemonics here. Hopefully these will help, sorry that we only got one day to go. Please post stuff that you think will help others.

Sumit

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