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Date Posted: 23:35:27 12/16/03 Tue
Author: Deb
Subject: Kwitka's Cancer Song [hope Kwitka doesn't mind.]

It’s beginning to look a lot like cancer
NITROGEN MUSTARDS
Take a look at MECHLORETHAMINE
Cross-linking guanines again
With CYCLOPHOSPHAMINE also you know

It’s beginning to look a lot like CARMUSTINE
And other NITROSOURIAS
But the non-synthetic to see is the STREPTOZO-TOCIN that will be on your diabetic door
A pair of SEMUSTINE and LOMUSTINE is the wish for brain tumors then
And platinum compounds like CARBOPLATIN is substituted for CIS nephrotoxin
And PROCARBAZINE can hardly wait to treat the Hodgkin’s

It’s beginning to look a lot like natural products
VINCA ALKALOIDS
That PACLITAXEL blocks cells in mitosis as
well
But does ETOPOSIDE bind to tublin? No!

It’s beginning to look a lot like ANTHRACYCLINES
BLEOMYCIN for a start
And the thing that will to DNA cling is that DOXORUBICIN
Just like DANORUBICIN
Right within G2!



Disclaimers:
1. Some of it may not seem to rhyme because I have no idea how to correctly pronounce these drugs, but it rhymes with the original Christmas lyrics in my head and that is what counts!
2. Streptozotocin causes diabetes, hence the diabetic door
3. Carboplatin is used in cases where cisplatin is toxic
4. Doxorubicin and Danorubicin don’t really “cling” to DNA but they do intercalate

It’s beginning to look a lot like Christmas
Everywhere you go
Take a look in the five and ten
Glistening once again
With candy canes and silver lanes aglow

It’s beginning to look a lot like Christmas
Toys in every store
But the prettiest sight to see is the holly that will be on your own front door
A pair of hop-a-long boot and a pistol that shoots is the wish of Barney and Ben
Dolls that can talk and will go for a walk is the hope of Janice and Jen
And Mom and Dad can hardly wait for school to start again

It’s beginning to look a lot like Christmas
Everywhere you go
There’s a tree in the grand hotel, one in the park as well
The sturdy kind that doesn’t mind the snow

It’s beginning to look a lot like Christmas

Soon the bells will start
And the thing that will make them ring is the
carol that you sing
Right within your heart
Right within your heart!

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